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Symptoms can include rash, itching, or, in severe cases, anaphylaxis

doi: 10.2337/db18-0696 87 BadmanMKPissiosPKennedyARKoukosGFlierJSMaratos-FlierE

GSH that is present in the lens in relatively high concentrations may compete with the amino acid residues for the unsaturated ketone derivative of kynurenine, thereby protecting the crystalline from modification

reported reduced expression of genes responsible for melanin synthesis in the hair folliclesuch as TYR, melan-A (MLANA), premelanosome protein (PMEL), TYRP1, SLC45A2, KIT, G proteincoupled receptor 143 (GPR143), and OCA2in patients with premature graying.15 UV radiation UV radiation plays an important role in hair graying by stimulating the production of free radicals

[47] Phospholipid hydroperoxide glutathione peroxidase