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Key risk factors for developing NAFLD include: Obesity , particularly central adiposity (excess abdominal fat) Type 2 diabetes mellitus and insulin resistance Dyslipidaemia (abnormal cholesterol and triglyceride levels) Metabolic syndrome (a cluster of conditions including hypertension, hyperglycaemia, and abnormal lipids) Sedentary lifestyle and poor dietary habits The underlying pathophysiology involves insulin resistance, which leads to increased delivery of free fatty acids to the liver, enhanced hepatic fat synthesis, and impaired fat oxidation
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2026 Mar 1:e70108
There is unfortunately no human data to date examining whether the ketogenic diet improves the efficacy, safety, or outcomes of immunotherapy in patients with GBM, either alone or in combination with standard treatments such as radiation therapy and temozolomide chemotherapy
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