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Available from: Ray-Coquard I, Leary A, Pignata S, Cropet C, Gonzlez-Martin A, Marth C, et al
In accordance with the glutathione activator hypothesis, only positively charged amino acids replace Lys105 in enzymatically active glutaredoxins, whereas in inactive isoforms and other members of the thioredoxin superfamily the activator candidate is often separated from the catalytic cysteine residue in the primary sequence or is replaced by uncharged residues 3,11,12 (Fig
Favretto DC, Pontin B, Moreira TR
The peptide does not reverse that trend, but it re-activates a signaling pathway that age progressively suppresses
CrossRef Association between HER2 heterogeneity and clinical outcomes of HER2-positive gastric cancer patients treated with trastuzumab Kyunghye Bang, Jaekyung Cheon, Young Soo Park, Hyung-Don Kim, Min-Hee Ryu, Yangsoon Park, Meesun Moon, Hyungeun Lee, Yoon-Koo Kang Gastric Cancer.2022
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