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Rare but Possible Side Effects of Glutathione Most side effects of glutathione occur due to incorrect dosage, lack of medical supervision, or non-standard formulations

This creates a rational decision for IP teams: reduce investment in late-stage secondary patent filings for small-molecule drugs and redirect that IP budget toward earlier-stage patents (where the compound is still within its pre-negotiation window) or toward biologic assets (where the 13-year clock preserves the value of secondary patents in years 9-13)

Azizi M, Kokabi H, Dianat-Moghadam H, Mehrmohammadi M