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Typically, the original structure of the amino acid is modified such that a COOH, or carboxyl, group is removed, whereas the -NH 3 + , or amine, group remains
1 Notably, one such medication, Wegovy, which has a main active ingredient of semaglutide, lists depression and suicidal ideation as potential side effects
These agents work by mimicking the action of the naturally occurring incretin hormone GLP-1, which is released from the intestine in response to food intake
Researchers have also found that oxidative stress may be the culprit behind some cases of major depressive disorder and other psychiatric disorders, including schizophrenia, bipolar, and psychosis