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A patient with unexplained fatigue should be worked up, not injected masking a B12 deficiency of unclear cause, or an unexamined thyroid problem, with a monthly shot is a real clinical risk
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Concurrently, inflamed adipose tissue secretes elevated free fatty acids, pro-inflammatory cytokines, and adipokines that exacerbate hepatic insulin resistance, lipotoxicity, and fibrogenesis [2]
The most frequent cause of sciatica is a herniated or bulging disc in the lower spine
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