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Menstrual cycle timing may affect response, with some women reporting better results when beginning protocols at specific cycle phases

Collagen is the protein that primarily makes up your skin, bones, and tendons

Vitamin B12 helps form red blood cells and improves the nervous system and metabolism

These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

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