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Clinical trials have demonstrated that Wegovy, when used alongside lifestyle modifications, can result in an average weight loss of approximately 15% of initial body weight over 68 weeks, as reported in the STEP 1 trial and referenced in NICE technology appraisal guidance (TA875)
Current Protocols in Protein Science / Editorial Board, John E
Start with a 0.75 mg subcutaneous injection as the initial dose once a week
Some individuals plateau at 10 mg and see no additional benefit from moving to 12.5 mg or 15 mg, while others require a full 15 mg weekly to reach their target
There is some instances of gall bladder stones or inflammation of the glands around the stomach and small intestine
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