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Aunque GLP-1 es conocido por su efecto incretnico, que comparte con el pptido insulinotrpico dependiente de la glucosa (GIP), la accin reguladora de la ingesta, esencial para su eficacia frente a la obesidad, tiene lugar merced a su interaccin con receptores localizados en el SNC1,5
Mounjaro was approved by the FDA in 2022 as a GIP and GLP-1 receptor agonist for improving blood sugar control in adults with type 2 diabetes, and subsequent trials went on to evaluate its effects specifically on body weight in people with obesity or overweight
I have had a patient say that her burps smelled like poop, Davisson said
Patient's started on a lower dose and then built up gradually to reduce side effects
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