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Growth hormone peaks during deep sleep, and inadequate rest impairs insulin sensitivity, increases cortisol (which promotes fat storage), and reduces the bodys ability to recover from the metabolic stress of rapid weight loss

[20] For nutritional deficiency without intrinsic-factor loss, shorter courses-such as 30-100 mcg intramuscularly daily for five to ten days followed by 100-200 mcg monthly-are often sufficient

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White C, Ji S, Cai H, et al (2012) Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders

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