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In those experiments, pretreatment with the peptide enhanced subsequent responses to growth hormone stimulation, including increased cell viability, elevated proliferating cell nuclear antigen (PCNA) expression, and greater JAK2 phosphorylation activity [5]

A randomized, double-blind trial of thymosin beta-4 in 72 patients with chronic venous stasis ulcers showed statistically significant wound closure compared to placebo at 3 months 12

More significant changes in elasticity and hyperpigmentation generally require three to six months of consistent use

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