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Proponents of B12 shots claim they turbocharge the metabolism (read: make you thinner), strengthen the immune system, and help cure fatigue, insomnia, even depression
Filtration removes some contaminants but doesn't sterilize
Immunological: Anti-inflammatory mechanism and cytokine suppression studies
Estrogen receptor signaling mechanisms
Other things like physical therapy, good sleep, better nutrition, and time can also explain why people feel better
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