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Some compounding pharmacies also offer sublingual (under-the-tongue) formulations, but these have not been extensively studied and the FDA has raised concerns about salt-form variations

Studies of gastric emptying suggest that long-acting agonists are subject to desensitization/tachyphylaxis of the effect, whereas short-acting agonists such as lixisenatide continue to inhibit gastric emptying even after repeated dosing [9]

Novo Nordisk continues to pursue innovative delivery models and strategic collaborations to meet people where they are, reaching more patients in more ways

It is thought that enzymes in the GI tract may break it apart before it can be absorbed

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