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The shapes of the individual MACE component hazard ratio curves were similar to that of the 3-point composite MACE endpoint, which indicates consistent findings across the components

According to the 2024 multi-society guidance (including the American Society of Anesthesiologists), most patients can continue GLP-1 receptor agonists perioperatively

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This may reflect the impact of reductions in renal perfusion pressure that have been associated with reduction in eGFR in both acute and chronic HF 30,31