semaglutide long term side effects 20 Ozempic and Wegovy You Should Know About Harvard and CDC study: Serious

Initial studies were conducted in animal models and progressed to human clinical observations, with particularly strong work on immune function, longevity markers, and circadian regulation

Significantly more women reported moderate or high sexual desire following bremelanotide vs placebo (p = 0.0114), and among women attempting intercourse within 24 hours of treatment, significantly more reported satisfaction with their level of sexual arousal following bremelanotide vs placebo (p = 0.0256) providing the foundational female sexual dysfunction dataset that directed PT-141 toward HSDD clinical development

FDA declared both shortages resolved in early 2026

GLP-1s, used to treat obesity, diabetes and heart problems, delay gastric emptying, and residual food or liquid in the stomach at the time of surgery with general anesthesia, may increase the risk for serious complications including aspiration

Whether this persists after stopping GLP-1 depends on weight maintenance see our rebound prevention guide