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Health Complications Because boiling water is necessary to brew coffee, a risk of these enemas is that they may cause burns in the bowel if the water is still too hot
642 In a multicenter, randomized, double-blind, placebo-controlled phase-3 clinical trial conducted in China, acetyllevocarnitine hydrochloride treatment for 24 weeks significantly improved symptoms and somatosensory symptoms in patients with DPN, with a treatment effect of 65% higher than placebo
Many published protocols recommend a window of no food intake before and after administration to optimize the research signal
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Thompson, D.A., et al
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