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In a pharmacological point of view, peptides given orally must be active only in the duodenum to limit potential indesirable effect

Although glutathione therapy is generally well tolerated, there are certain situations in which its administration may be contraindicated or require medical evaluation and supervision

Int J Mol Sci 16(8):1719317230 Panner Selvam MK, Sengupta P, Agarwal A (2020) Sperm DNA Fragmentation and Male Infertility

Glutathione can prevent and repair oxidative damage by capturing free radicals throughout the body and recharging other antioxidants, thus preventing chronic disease and inflammation

The EFSA bases their recommendations on intake , as distinct from the amount absorbed used by the IOM