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Nausea, vomiting, diarrhea, constipation, and appetite changes are the main reported symptoms

Key Considerations for Timing: Take B12 and iron supplements at different times to avoid possible interactions

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In MCF-7 cells, it induced apoptosis and blocked cell cycle progression, hence mediating cell death ( in vitro IC 50 concentrations may not directly reflect clinically achievable plasma or tissue levels, and translational interpretation requires pharmacokinetic validation