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Although native human GLP-1 increases insulin secretion and decreases glucagon secretion in a glucose-dependent manner, its short t makes it unsuitable for clinical use in type 2 diabetes [19, 20]
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Given the strong association between MASLD and cardiovascular pathology, that represents the primary cause of death in this population, the cardioprotective benefits of GLP-1 RAs provide important additional clinical value beyond hepatic benefits
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doi: 10.1159/000449095 2 SenderRFuchsSMiloR
