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These progenitors migrate into the brain early during development, where they then differentiate into functional microglial cells

Certain therapies may not be appropriate during pregnancy or breastfeeding

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Indian J Exp Biol 40:12404, PMID:13677625 Morris G, Maes M (2013) Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

We have other data from individuals with type two diabetes who have been using these drugs much longer, although weight loss was not the primary outcome, more diabetes control, and they tend to maintain a lower body weight as well, it's not as clear whether it's the same weight