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Weight loss typically continues, with clinical trials showing that semaglutide 2.4 mg (Wegovy) produces average weight loss of approximately 15% by week 68, while tirzepatide (Zepbound) has demonstrated weight loss of approximately 15-21% across different doses by week 72
It works through several mechanisms: it slows gastric emptying (so food stays in your stomach longer and you feel full sooner), it reduces appetite signals in the brain, and it improves insulin sensitivity
This test is not a pharmacogenomic test of antidepressant metabolism
Excluding cases with missing or incomparable dose unit data (dose_unit column as MG/M**2 or IU), effective dose data were available for 34,098 cases
In large studies, people on the high-dose injection lost about 15% to 20% of their body weight
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