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This is a localised and transient chemical response, not an allergic reaction and not a sign of peptide instability
Yes, rarely, Prolia (denosumab) can cause bad side effects such as: Serious allergic reactions with low blood pressure, throat tightness, trouble breathing, swelling of the face, eyes, lips, tongue or throat, skin rash, hives, and itching
FDAs 2024 review summarized several early human studies and the later OPTIONS study
Total peptide content 10mg per vial
Both modifications are studied in vitro for the resistance they confer to exopeptidase cleavage and for their effect on measured peptide half-life in serum-stability assays
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