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The STEP UP trial in people with obesity tested the higher dose of semaglutide (7.2mg) against the 2.4mg dose and placebo over 72 weeks in over 1,400 adults living with obesity without type 2 diabetes

doi:10.1038/laban0512-129 pmid:22517091 Bondolfi L, Ermini F, Long JM, Ingram DK, Jucker M (2004) Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice

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KPV: The Inflammation Extinguisher KPV is a tripeptide made of three amino acids- Lysine, Proline, and Valine

Recently, semaglutide treatment demonstrated a 1.5% lower risk in absolute risk in the 3P-MACE compared to placebo (6.5% vs