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In spite of being fed a high-fat diet, these mice gained less weight and their leptin receptors remained intact
Weight loss ranging from 18.3% (in MC4R mutation carriers) to 43.5 pounds (in the highest dose group) over 72 weeks in obese patients
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This isn't a spike
Rotate sites weekly to reduce lipohypertrophy (lumps under the skin from repeated injections in the same spot)
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