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doi:10.1038/s41366-020-00728-8

Diarrhoea is a very common side effect of Ozempic

This step might involve acid-base catalysis by the active-site cysteinyl thiolate (which could explain an effect of the second cysteinyl residue), and/or the conserved lysine residue, yielding GS in analogy to glutathione transferases (Fig