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BSO treatment was not included, because this already induced a significant oxidative stress response (data no shown)
The efficacy of subcutaneous semaglutide was established in the phase III SUSTAIN program (SUSTAIN 15 and 7), in which significant reductions in mean glycated hemoglobin (HbA 1c ) and body weight were demonstrated against placebo and a variety of active comparators in multiple patient groups with T2D [26,27,28,29,30,31,32,33]
Formulations cosmtiques : Gnralement inclus des concentrations de 0.1 % 2 %, selon leffet claircissant souhait
The most common experimental dose in animal studies (Sikiric et al.) is 10 g/kg/day intraperitoneally or orally in rats