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It also activates p38 MARK, ERK1/2 cascade, and JNK cascade, which promotes apoptosis and inflammation (Potilinski et al., 2020)
Receptors are expressed in multiple nuclei of the hypothalamus and brainstem, where central mechanisms suppress appetite and regulate energy intake and expenditure (7174)
NADPH oxidase complexes are composed of protein subunits that interact to form the functional enzyme complex
Sources Zhang, L., et al
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