SUA is taken up by OAT1/OAT3 into tubular cell, then intracellular UA is excreted by NPT4 into the urinary lumen (Mller and Sheikh, 1982
This unanticipated outcome may provide critical clues to the mechanism underlying GEP44-mediated weight loss observed in experiments performed in vivo
Metformin, a drug used to treat type 2 diabetes, can also decrease absorption of B12 in the small intestine of 10 percent to 30 percent of patients
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