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Int J Cancer 2008

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Clinical red flags that suggest cardiac origin include: sudden onset of severe symptoms, radiation to typical cardiac distribution areas, associated autonomic symptoms (sweating, pallor), exertional provocation, and risk factors such as prior cardiovascular disease, long-standing diabetes, hypertension, dyslipidemia, or family history of premature coronary disease

O mecanismo de ao mediado por dois receptores: o receptor de grelina (GHSR-1a) e, de forma modesta, o receptor de GHS (Growth Hormone Secretagogue Receptor)

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