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J Biol Chem 265:1995519960 Fedorova M, Griesser E, Vemula V, Weber D, Ni Z, Hoffmann R (2014) Protein and lipid carbonylation in cellular model of nitrosative stress: mass spectrometry, biochemistry and microscopy study

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Orforglipron Orforglipron is a once-daily, oral, non-peptide GLP-1 RA (small molecule) which interacts with the GLP-1 receptor in a slightly different manner compared to native GLP-1

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We dont have much data yet and the Phase I so far was mixed, with Phase II data coming this year