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Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion

Always consult a qualified healthcare professional before starting, stopping, or changing any prescription treatment or health program

Current therapeutic strategies remain constrained by limited cell specificity, timing sensitivity, and safety concerns, underscoring the need for precision-guided approaches

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It just depends on each provincial review of whether they include it or dont include it as part of their drug benefits for people who are eligible for the drug benefit program. Small also added that it makes sense economically to include generic GLP-1 drugs into insurance plans