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The results showed high heterogeneity of weight loss from the baseline weight between individuals even at the highest dose of tirzepatide 38.4 to 9.0 kg and mean 22.1 kg
J Clin Endocrinol Metab 91(9):33443348 Afman LA, Lievers KJA, van der Put NMJ, Trijbels FJM, Blom HJ (2002) Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects
That is the price of activating GLP-1 receptors
Patients need to understand that GLP-1s work best as part of a comprehensive plan. They should be working with a nutritionist, increasing physical activity, and thinking long-term
1 , e00009 (2018)
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