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Fats and carbohydrates blunt the GH response

The gradual increase lets your body adapt to triple-receptor activation incrementally, reducing side effects that would be severe at full dose from day one

GLP-1 medications cause constipation by slowing gastric emptying and overall gut transit time Macrogol preparations retain water in stool and are recommended for long-term use with GLP-1 therapy Bulk-forming laxatives like ispaghula husk are first-line treatment according to NICE guidance Adequate hydration (1.52 litres daily) is essential when using laxatives with GLP-1 medications Patients should seek medical advice if constipation persists beyond 12 weeks despite treatment Table of Contents Have questions about Wegovy

Lorenz M, Owens D, Raccah D, et al