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doi: 10.1111/dom.2011.13.issue-1 211 de LemosJALinetzkyBle RouxCWLaffinLJVongpatanasinWFanLet al

Due to this cleavage by DPP-4, GLP-1 (7-36) amide has a very short half-life in vivo between 1 2 minutes 6,7 , which reduces the biological effects of active GLP-1 (7-36) amide 5

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43 On the other hand, another review of 26 studies in osteoarthritic dogs found undenatured type II collagen supplementation, at a typical dose of 10 mg per day for one to five months, increased mobility and physical activity, and reduced lameness