The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88
A key hypothesis we are studying here is that in endometriosis, a pro-oxidant microenvironment in the local vicinity of the follicle created by an unbalanced redox state detrimentally impacts the quality of oocytes, sperm, and embryos, hampering their cellular function, jeopardizing their viability, and that this is a fundamental underlying cause of diminished fertility with endometriosis
Additionally, leveraging NRF2 activation can bolster cellular antioxidant defenses, further mitigating the pathological effects of ferroptosis
Discard any solution showing cloudiness, particles, or unusual coloration rather than risking use of compromised material
weight loss/weight gain ( n = 6)
