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10.1016/j.vph.2018.02.010 147 VukojevicJ.VrdoljakB.MalekinusicD.SiroglavicM.MilavicM.KolencD.et al (2020)
GLP-1 receptors are found throughout the body and within the brain and can have multi-system effects, including our reward-based eating
Who should skip GLP-1 supplements People with significant weight-related health risks, including type 2 diabetes, cardiovascular disease, or obesity-related complications, should not rely on supplements when pharmaceutical options exist that produce faster, stronger, better-documented results
This protective action is attributed to the role of lactate as an alternative energy substrate, whereby its conversion to pyruvate enables mitochondrial oxidation once oxygen is restored (157)
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