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DSIP may be beneficial in some chronic pain conditions (Pollard BJ, 2001)

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However, the metabolism of phenytoin may be saturated based on its zero-order kinetics, so phenytoin metabolism cannot increase any higher

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Those who are concerned or particularly sensitive can request additional pre-injection numbing injections with lidocaine or can use ice prior to injection to numb the treatment area (avoiding the initial pin-prick of Vollure)

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