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Due to the loss of the brain privilege for vitamin B2 supply, this inherited condition may be particularly relevant for CNS diseases such as migraine, brain ischemia, traumatic brain injury, neurodegenerative disorders (especially Parkinson and Alzheimers diseases), epilepsy, multiple sclerosis, and for Guillain-Barr syndrome, myasthenia, and mitochondrial myopathies
Chronic inflammationinflammatory cells include primarily mononuclear cell (largely lymphocytes, macrophages) and may include fibrosis and oval cell hyperplasia
Current understanding of dysbiosis in disease in human and animal models
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