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Injections deliver B12 directly into the bloodstream, making them far more effective for those with deficiency
doi:10.1128/AEM.60.5.1495-1499.1994
This paradoxical response affects some patients receiving hydroxocobalamin treatment for vitamin B12 deficiency
[2] Patients should contact their GP if they experience: Side effects from B12 injections (though these are rare and usually mild) Difficulty attending scheduled injection appointments, as missed doses may lead to symptom recurrence New symptoms developing during treatment Concerns about treatment effectiveness or duration Changes in other medications that might affect B12 absorption Suspected adverse reactions to B12 treatment can be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)
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