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however, their broader applicability is constrained by limited tissue penetration of light, which may restrict their use primarily to superficial or otherwise accessible tumors unless complemented by emerging deep-penetration activation strategies, such as X-ray-activated systems or approaches based on NIR-II light [156]

Biol Trace Elem Res 143:17581776

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Although normal electron transport in mitochondria involves four-electron reduction of O 2 to water, partial reduction reactions occur under physiological conditions, causing release of superoxide anion and hydrogen peroxide (H 2 O 2 )

Patients should report adverse reactions via the MHRA Yellow Card scheme and seek emergency care for anaphylaxis symptoms