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F., Nadzirin, N., Velankar, S

10.1016/j.celrep.2017.10.008 230

The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells

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In its Complete Response Letter, FDA said results from the Phase III ROMAN trial, in combination with the GT-201 trial, were not sufficiently persuasive to establish substantial evidence of avasopasems effectiveness and safety in reducing these mouth sores