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Menopause and hormonal shifts: Hormonal changes, especially declining estrogen, can slow metabolism, increase fat storage, and reduce muscle mass, all of which make weight loss harder

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Contact your physician if you experience profuse sweating that soaks through clothing, occurs primarily at night (night sweats), or is accompanied by other concerning symptoms such as fever, unexplained weight loss beyond expected treatment effects, chest pain, palpitations, or shortness of breath

If you miss or forget to take oral semaglutide often, tell your provider especially if youre not losing weight or seeing results