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Over-activation and/or chronic activation of microglia cause excessive and uncontrolled neuroinflammatory responses, leading to a self-perpetuating vicious cycle of neurodegeneration (14)

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Adverse reactions are possible and may pose a risk to patients

Nat Rev Nephrol 17 , 227244 (2021)

Reduced Joint Inflammation: In animal models of arthritis, daily administration of BPC-157 has been shown to reduce joint inflammation, with benefits observed for up to one year