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Caspase-3-dependent cleavage of the glutamate-L-cysteine ligase catalytic subunit during apoptotic cell death

Taken together, the evidence reviewed herein supports the view that melatonin constitutes a unifying biological axis through which circadian rhythms, sleep, nutrition, and oxidative balance intersect during aging

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Figure 2 2 , and adiponectin activate PKA-PKC/MAPK-, Ca + -, and AMPK-dependent pathways to modulate cholesterol transport, protein synthesis, progesterone production, and luteal cell survival or apoptosis