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Serotoninnorepinephrine reuptake inhibitors (SNRIs) inhibit reuptake of serotonin and norepinephrine, which increases descending inhibition and reduces pain associated with DPN [43]
Oral supplements have limited absorption compared to IV injections, but may still offer antioxidant support
These creams work mainly on the surface of the skin and absorb in very small amounts, making them generally safe for daily under-eye care
Allow a refrigerated or frozen vial to reach room temperature before opening, since introducing solvent into a cold vial encourages condensation
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