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JAD 19:311

The study, which ended prematurely due to a higher mortality rate in the intensive treatment group, failed to report significant reduction in major cardiovascular events, giving a notion that intensive therapy was associated with significant harm in high risk patients [6]

Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjoth TV, et al

Any medication used is simply a tool to help with weight loss

197 For instance, increased blood urea concentrations can alter the microbiome, resulting in the increased generation of toxic metabolites from the gastrointestinal tract as well as an increased tendency for toxins to cross the gut barrier, which can promote further kidney injury