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They bind to receptors in the pancreas, brain, and gastrointestinal tract, stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying (though this effect may diminish over time with continued use)

[36] Allergic reactions to melatonin, while relatively uncommon, can range from mild skin reactions to more severe systemic responses requiring immediate medical attention

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Efficacy of exenatide administered twice daily in body mass index reduction in patients with type 2 diabetes mellitus

Talk with your provider about ways to prevent or manage diabetes and control other risk factors