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Capitalizing on this, a ruthenium complex with an iodo, p-cymene, and phenylazopyridine ligand Ru(II)-OH was designed
Proc Natl Acad Sci 111(25):93199324
It is absorbed primarily from the small intestine through passive transcellular diffusion, a mechanism that is inherently less sensitive to food effects than the SNAC-mediated gastric absorption pathway used by oral semaglutide
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