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307,413 In terms of apoptosis inhibition, GLP-1 activates the PI3K/Akt signaling pathway, enhances the expression of the anti-apoptotic protein Bcl-2, and inhibits the activation of caspase family proteins, reducing cell apoptosis
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When ketosis is added to semaglutide treatment, the theoretical and observed weight loss rate tends to increase because both approaches are simultaneously reducing caloric intake through appetite suppression, shifting metabolism toward fat oxidation, and improving insulin sensitivity
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