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NSAIDs inhibit COX-1-mediated prostaglandin synthesis, reducing the protective mucus layer in the stomach and duodenum
Glucagon-like-peptide-2 (GLP-2) is a similar compound that is typically not considered an incretin due to its lack of glycemic effects
DPP4 expression and its regulation Dipeptidyl-peptidase 4 is ubiquitously expressed on numerous different cell types among which are epithelial cells, fibroblasts, and leukocyte subsets
Working to reverse the US epidemicat a glance 2016
The primary endpoint was major adverse cardiovascular events (MACE), defined as cardiovascular death, nonfatal heart attack, or nonfatal stroke
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